ISO/TC215/SC1 was established in 2019, and ISO/TC215/SC1 aims at standardization of computable data, information, and knowledge, including their representation and metadata, for the application of omics, including but not limited to genomics, phenomics and proteomics, to support human health and clinical research. 18 countries joined the ISO/TC215/SC1 and have actively worked on standarization of clinical sequencing. Five ISO standards have been already published, and seven ISO standards have been under development.