[1P-0023] Comprehensive deletions and inversions by genome engineering uncover the regulation of chromatin topology of the Tfap2c-Bmp7 locus.

〇Taro Tsujimura^1,2, Osamu Takase^1,2, Mana Idei^1,2, Masahiro Yoshikawa^1,2, Masaomi Nangaku¹, Tsuyoshi Takato², Keiichi Hishikawa^1,2 (1.Dept. of Adv. Nephrol. and Regen. Med., Div. of Nephrol. and Endocrinol., Univ. of Tokyo Hosp., 2.Div. of Tissue Eng., Univ. of Tokyo Hosp.)

Chromatin conformation, genome engineering, CTCF, CRISPR, enhancer