[1P-0048] The quest for a key features of the kinase activity of human topoisomerase I: characterization of interacting domains of topoisomerase I and SRSF1 splicing factor

Agnieszka Sztyler¹, Kaja Przygonska², Monika Szewczyk¹, Katarzyna Grudziaz³, 〇Takao Ishikawa¹ (1.Dept. of Mol. Biol., Fac. of Biol., Univ. of Warsaw, Poland, 2.Dept. of Biophys., Inst. of Biochem. and Biophhys., Polish Acad. of Sci., 3.Biol. and Chem. Res. Cent., Fac. of Chem., Univ. of Warsaw, Poland)

intrinsically disordered domain, kinase, phosphorylation, topoisomerase I, nuclear protein