The Molecular Biology Society of Japan

[1P-0060] Discovery of potent, reversible and specific chemical inhibitors of Midasin, an essential AAA+ protein for ribosome biogenesis

〇Shigehiro A. Kawashima1,2, Zhen Chen2, Yuki Aoi1, Yuki Kobayashi1, Paul Nurse2,3, Tarun M. Kapoor2 (1.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 2.The Rockefeller University, 3.The Francis Crick Institute)

AAA+ protein, Midasin, ribosome biogenesis, chemical genetic screen, small molecule inhibitors

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