[1P-0563] LRRK1 plays an essential role in B-cell responses via CARMA1-dependent NF-ĸB signaling.

〇Keiko Morimoto¹, Yoshihiro Baba^2,3, Hisaaki Shinohara⁴, Tomohiro Kurosaki^2,3, Toshihiko Toyofuku⁵, Atsushi Kumanogoh¹ (1.Dept. of Respiratory Medicine, Allergy and Rheumatic Disease, Grad. Sch. of Med., Univ. of Osaka, 2.Lab. for Lymphocyte Differentiation, IFReC, Univ. of Osaka, 3.Lab. for Lymphocyte Differentiation, IMS, RIKEN, 4.Lab. for Integrated Cellular Systems, IMS, RIKEN, 5.Dept. of Immunology and Regenerative Medicine, Grad. Sch. of Med., Univ. of Osaka)

LRRK, NF-kappa B, BCR, CARMA1