[1P-0671] Studies on the creation of novel antitumor drugs targeting the key enzyme of NAD^＋biosynthesis , nicotinamide phosphoribosyltransferase

〇Kiyotaka Katsuragi¹, Akira Sato^1,2, Yoko Ogino¹, Yuri Shibasaki¹, Yusuke Takai¹, Atsushi Yoshimori³, Takahiro Oyama⁴, Hideaki Abe⁴, Sei-ichi Tanuma^1,2 (1.Dept. of Biochem., Fac. of Pharm. Sci., Tokyo Univ. of Sci., 2.Genome & Drug Res. Ctr., Tokyo Univ. of Sci., 3.Inst. for Theoretical Med., Inc., 4.Hinoki Shinyaku Co., Ltd)

NAMPT/NmPRT , NAD^＋biosynthetic pathway, NmPRT inhibitor