Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis (MALA)

Tomoko Oyaizu-Toramaru; Tomohiro Suhara; Noriyo Hayakawa; Takashi Nakamura; Shizuka Minamishima; Kyoji Yamaguchi; Takako Hishiki; Hiroshi Morisaki; Makoto Suematsu; Yoji Andrew Minamishima

[1P-0700] Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis (MALA)

Tomoko Oyaizu-Toramaru^1,2, Tomohiro Suhara^1,2, Noriyo Hayakawa^1,3, Takashi Nakamura¹, Shizuka Minamishima², Kyoji Yamaguchi⁴, Takako Hishiki^1,3, Hiroshi Morisaki², Makoto Suematsu¹, 〇Yoji Andrew Minamishima^1,2,5 (1.Dep. of Biochem., Keio Univ. Sch. of Med., 2.Dep. of Anesth., Keio Univ. Sch. of Med., 3.Translational Res. CTR., Keio Univ. Sch. of Med., 4.Rare Dis. & LCM lab., Daichi Sankyo Co. Ltd., 5.Med. Inst. Bioreg., Kyushu Univ.)

低酸素, 代謝, 乳酸アシドーシス, PHD, メトホルミン

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The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0700] Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis (MALA)

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