The Molecular Biology Society of Japan

[1P-0721(2AS14-5)] Aggregation propensity and structural change of TDP-43 carrying ALS-linked mutation in intrinsically disordered region in live cells

〇Akira Kitamura1, Sachiko Yuno1,2, Ai Shibasaki1,2, Kayo Takeda1,2, Fusako Gan1,3, Makoto Oura1,2, Johtaro Yamamoto1, Masataka Kinjo1 (1.Lab. of Mol. Cell Dyn., Fac. of Adv. Life Sci., Hokkaido Univ., 2.Grad. Sch. of Life Sci., Hokkaido Univ., 3.Sch. of Sci., Hokkaido Univ.)

TAR-RNA/DNA binding protein 43 kDa, amyotrophic lateral sclerosis, intrinsically disordered region, RNA-binding protein, Fluorescence imaging

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