Importance of the side chain at position 296 of antibody Fc in interactions with Fc&#947;RIIIa and other Fc&#947; receptors

Yuya Isoda; Hirokazu Yagi; Tadashi Satoh; Mami Shibata-Koyama; Kazuhiro Masuda; Mitsuo Satoh; Koichi Kato; Shigeru Iida

[1P-0819] Importance of the side chain at position 296 of antibody Fc in interactions with FcγRIIIa and other Fcγ receptors

〇Yuya Isoda¹, Hirokazu Yagi², Tadashi Satoh^2,3, Mami Shibata-Koyama¹, Kazuhiro Masuda¹, Mitsuo Satoh¹, Koichi Kato^2,4, Shigeru Iida¹ (1.Kyowa Hakko Kirin Co., Ltd., 2.Grad. Sch. of Pharm. Sci., Nagoya City Univ., 3.JST, PRESTO, 4.Inst. Mol. Sci. and Okazaki Inst. Integr. Biosci., Natl. Inst. Nat. Sci.)

Antibody, FcγR, ADCC, Fucose, Tyr-296

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The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0819] Importance of the side chain at position 296 of antibody Fc in interactions with FcγRIIIa and other Fcγ receptors

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