[2P-0156] NSD1 haploinsufficiency evokes DNA hypomethylation at imprinted DMRs and the increased expression of imprinted genes.

〇Hidetaka Watanabe¹, Ken Higasimoto¹, Noriko Miyake², Toshiyuki Maeda¹, Hidenori Hidaka¹, Saori Aoki¹, Hitomi Yatsuki¹, Kenichi Nishioka¹, Keiichiro Jyo¹, Sumiyo Morita³, Takuro Horii³, Mika Kimura³, Izuho Hatada³, Naomichi Matsumoto², Hidenobu Soejima¹ (1.Division of Molecular Genetics & Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 2.Yokohama City University, Graduate School of Medicine, Department of Human Genetics, 3.Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University)