The Molecular Biology Society of Japan

[2P-0240(2PS7-7)] Hyper-activation of nonsense-mediated mRNA decay in fragile X mental retardation protein-depleted cells

〇Tatsuaki Kurosaki1,3, Chris Proschel2, Lynne E. Maquat1,3 (1.Dept. of Biochem. & Biophys., Sch. of Med. & Dent., Univ. of Rochester, 2.Dept. of Biomed. Genet., Sch. of Med. & Dent., Univ. of Rochester, 3.Center of RNA Biol., Univ. of Rochester)

Nonsense-mediated mRNA decay, Fragile X mental retardation syndrome, UPF1, FMRP

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