[2P-0572] Haploinsufficiency of the synaptic suppressor MDGA2 elevated excitatory/inhibitory ratio to cause autism-like behavior.

〇Tohru Yamamoto¹, Steven A. Connor², Yasushi Kishimoto³, Ina Ammendrup-Johnsen², Naokazu Kurihara³, Chiaki Murayama^1,4, Toshiharu Suzuki⁴, Ann Marie Craig² (1.Lab. of Mol. Neurobiol., Fac. of Med., Kagawa Univ., 2.Univ. of British Columbia, 3.Fac. of Kagawa Pharm., Tokushima Bunri Univ., 4.Lab. of Neuroscience, Fac. of Pharm., Hokkaido Univ.)

ASD, E/I balance, Neuroligin, MDGA2