Alteration of oligomeric states and subcellular localization of ALS2 mutants underlie the pathogenesis of <I>ALS2</I>-linked motor neuron diseases

Kai Sato; Kyoko Suzuki-Utsunomiya; Yui Hiratsuka; Shun Mitsui; Suzuka Ono; Asako Otomo; Shinji Hadano

[2P-0578] Alteration of oligomeric states and subcellular localization of ALS2 mutants underlie the pathogenesis of ALS2-linked motor neuron diseases

〇Kai Sato¹, Kyoko Suzuki-Utsunomiya¹, Yui Hiratsuka¹, Shun Mitsui¹, Suzuka Ono¹, Asako Otomo¹, Shinji Hadano¹ (1.Dept Mol Life Sci,Tokai Univ Sch of Med)

ALS, ALS2, Rab5, EarlyEndsome, Macropinosome

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The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0578] Alteration of oligomeric states and subcellular localization of ALS2 mutants underlie the pathogenesis of ALS2-linked motor neuron diseases

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