[2P-0728] The novel YAP1 activator induces a YAP1-p73 pathway-dependent apoptosis in human multiple myeloma cells

〇Junichi Maruyama¹, Xinliang Jiang¹, Hiroaki Iwasa¹, Mari Ishigami-Yuasa^2,3, Hiroyuki Kagechika^2,3, Hiroshi Nishina⁴, Yutaka Hata¹ (1.Medical Biochemistry, Grad. Sch. Med. Dent. Sci., Tokyo Medical and Dental Univ., 2.Chemical Biology Screening Center, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., 3.Organic and Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ., 4.Developmental and Regenerative Biology, Medical Research Institute, Tokyo Medical and Dental Univ.)

Hippo pathway, YAP1, Multiple myeloma