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[3AS13-8] Dependence on the mitochondrial MTHFD2-mediated purine synthetic pathway in lung cancer

〇Noriko Gotoh1,2, Tatsunori Nishimura1, Asuka Nakata1, Shin-ichi Horike3, Kaori Saitoh4, Keiko Kato4, Kaori Igarashi4, Susumu Kohno5, Chiaki Takahashi5, Tomoyoshi Soga4, Arinobu Tojo2 (1.Div. of Cancer Cell Biol., Cancer Res. Inst., Kanazawa Univ., 2.Div. of Mol. Therapy, Inst. Med. Sci. of Univ. Tokyo, 3.Div. of Functional Genomics, Advanced Sci. Re. Center, Kanazawa Univ., 4.Inst. for Advanced Biosci., Keio Univ., 5.Div. of Oncol. Mol. Biol., Cancer Res. Inst., Kanazawa Univ.)

代謝, がん幹細胞, メタボローム, 治療抵抗性

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