[3P-0115] Direct single-molecule observations of the initiation of SV40 DNA replication under a negative supercoil state of DNA

〇Shunsuke Takahashi^1,6, Shinya Motooka¹, Shohei Kawasaki¹, Hirofumi Kurita², Takeshi Mizuno³, Shun-ichi Matsuura⁴, Fumio Hanaoka⁵, Akira Mizuno², Masahiko Oshige¹, Shinji Katsura¹ (1.Dept. of Envi. Eng. Sci., Gunma Univ., Gunma, 2.Dept. of Chem. and Envi. Eng., Toyohashi Univ. of Tech., Aichi, 3.RIKEN, 4.AIST, 5.Inst. for Biomol. Sci., Fac. of Sci., Gakushuin Univ., Tokyo, 6.JSPS Research Fellow)

１分子観察, 負の超らせん, DNA鎖巻き戻し反応, ラージT抗原, DNA複製開始