[3P-0117] Establishment of DNA polymerase δR506H mutants in MSH2-null HeLa MR cell using CRISPR/Cas9 genome editing system

〇Yingxia Song^1,2, Kyoko Hidaka³, Yoshimichi Nakatsu², Shinya Oda⁴, Genki Hayashida^2,5, Ryosuke Fujikane⁶, Masumi Hidaka⁶, Teruhisa Tsuzuki² (1.Grad. Sch. Med. Sci., Kyushu Univ., 2.Dept. Med. Biophys. Radiat. Biol., Fac. Med. Sci., Kyushu Univ., 3.Cetr. for Fundament. Ed., Univ. of Kitakyushu, 4.Institute for Clinical Research, National Kyushu Cancer Center, 5.Grad. Sch. System Life Sci., Kyushu Univ., 6.Dept. Physiol. Sci. Mol. Biol., Fukuoka Dent. Col.)

Proofreading, Microsatellite instability, Mismatch repair