[3P-0468(1AS15-3)] GFRA2, a member of GDNF receptor family, mediates cardiomyocyte differentiation and compaction of ventricular myocardial layer in a RET-independent signal cascade.

〇Kenta Yashiro^1,3, Hidekazu Ishida^2,3, Rie Saba^1,3, Ioannis Kokkinopoulos³, Masakazu Hashimoto⁴, Osamu Yamaguchi⁶, Leo Dunkel³, Tinker Andrew³, Shigetoyo Kogaki², Yasushi Sakata⁶, Anna-Katerina Hadjantonakis⁴, Yoshiki Sawa⁷, Hiroshi Sasaki⁵, Keiichi Ozono², Ken Suzuki³ (1.Cardiovasc. Reg. Ther., Osaka Univ. Grad. Sch. of Med., 2.Dep. of Paed., Osaka Univ. Grad. Sch of Med., 3.William Harvey Res. Instit., Barts & The London Sch. of Med. and Dent., Queen Mary Univ. of London, 4.Dev. Biol. Prog., Memorial Sloan Kettering Cancer Center, 5.Lab. for Embryogenesis, Osaka Univ. Grad. Sch. of Frontier Biosciences, 6.Dep. of Cardiovasc Med., Osaka Univ. Grad. Sch. of Med., 7.Dep. of Cardiovasc Surg., Osaka Univ. Grad. Sch. of Med.)

心臓前駆細胞, 神経栄養因子受容体GFRA2, 心筋分化, 心室緻密化障害心筋症, RET非依存的新規シグナル経路