[3P-0586] CDKL5 controls postsynaptic NMDA receptor localization and regulates memory, emotion and seizure susceptibility

〇Takuto Murakami¹, Kosuke Okuda¹, Shizuka Kobayashi², Masahiro Fukaya³, Keizo Takao^4,5, Shinji Omi¹, Aya Watanabe¹, Mai Hagiwara¹, Hiroyuki Sakagami³, Masashi Mizuguchi¹, Tsuyoshi Miyakawa^4,6, Toshiya Manabe², Teruyuki Tanaka¹ (1.Dept Developmental Med Sci. Univ of Tokyo, Tokyo, 2.Division of Neuronal Network, Dept. of Basic Medical Sciences, The Univ. of Tokyo, Tokyo, 3.Dept. of Anatomy, Kitasato Univ. School of Medicine, Sagamihara, 4.Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki, 5.Division of Animal Resources and Development, Life Science Research Center, Univ of Toyama, 6.Division of Systems Medical Science, Fujita Health University)

NMDA receptor, epilepsy, phosphorylation, Rett syndrome