The Molecular Biology Society of Japan

[3P-0725] Formal modeling of clonal expansion of HTLV–1—infected cells in adult T–cell leukemia using high–throughput sequencing data

〇Amir Farmanbar1,2, Sanaz Firouzi1, Sung-Joon Park2, Kaoru Uchimaru1,3, Toshiki Watanabe1,4, Kenta Nakai1,2 (1.Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 2.Laboratory of Functional Analysis in silico, Human Genome Center, Institute of Medical Science, 3.Hematology/Oncology, Research Hospital, Institute of Medical Sciences, The University of Tokyo, 4.Institute of Medical Science and Departments of Immunology and Medicine, St. Marianna University School of Medicine)

human T-cell leukemia virus type-1, adult T-cell leukemia, integration site, next generation sequencing, mathematical computational modeling

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