[3P-0725] Formal modeling of clonal expansion of HTLV–1—infected cells in adult T–cell leukemia using high–throughput sequencing data

〇Amir Farmanbar^1,2、Sanaz Firouzi¹、Sung-Joon Park²、Kaoru Uchimaru^1,3、Toshiki Watanabe^1,4、Kenta Nakai^1,2 (1.Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo、2.Laboratory of Functional Analysis in silico, Human Genome Center, Institute of Medical Science、3.Hematology/Oncology, Research Hospital, Institute of Medical Sciences, The University of Tokyo、4.Institute of Medical Science and Departments of Immunology and Medicine, St. Marianna University School of Medicine)

human T-cell leukemia virus type-1, adult T-cell leukemia, integration site, next generation sequencing, mathematical computational modeling