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[3PS6-6(2P-0642)] Relationship between dysbiosis and tertiary structual deficiency of α-defensin involving pathological progression in SAMP1/YitFc, a murine model of Crohn's disease

〇Yu Shimizu1, Kiminori Nakamura1,2, Aki Yoshii1, Mani Kikuchi1,2, Naoya Sakuragi1,2, Tokiyoshi Ayabe1,2 (1.Innate Immunity Lab., Grad Sch. of Life Sci., Hokkaido Univ., 2.Innate Immunity Lab., Dept. of Cell Biol. Sci., Faculty of Adv. Life Sci., Hokkaido Univ.)

α-defensin, Crohn's disease, model mouse, tertiary structure, dysbiosis

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