REF-dependent gross chromosomal rearrangements in centromeres

Akiko Okita¹, Dayalini Weerasekara¹, Tatsuro Takahashi¹, Hisao Masukata¹, 〇Takuro Nakagawa¹ (1.Dept of Biol Sci, Grad Sch of Sci, Osaka Univ)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0149(3PS3-7)] The synaptonemal complex protein SYCE2 promotes DNA damage response and repair by affecting the function of HP1

〇Noriko Hosoya¹, Kiyoshi Miyagawa¹ (1.Lab. of Mol. Radiol., Grad. Sch. of Med., the Univ. of Tokyo)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0150] Chromatin dynamics regulating DNA damage recognition

〇Erina Kakumu^1,2, Seiya Nakanishi^1,2, Wataru Sakai^1,2, Naoko Adachi¹, Naoaki Saito¹, Toshio Mori³, Hiroshi Kimura⁴, Hitoshi Kurumizaka⁵, Kaoru Sugasawa^1,2 (1.Biosignal Res. Ctr., Kobe Univ., 2.Grad. Sch. Sci., Kobe Univ., 3.Nara Med. Univ., 4.Grad. Sch. Biosci. Biotechnol., Tokyo Inst. Technol., 5.Grad. Sch. Adv. Sci. Engineer., Waseda Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0151] Smarcad1/Fun30 promotes nucleosome exclusion to facilitate eukaryotic mismatch repair

〇Riki Terui¹, Kanae Taki¹, Koji Nagao², Seiji Tanaka^3,4, Takuro Nakagawa¹, Chikashi Obuse², Hisao Masukata¹, Tatsuro Takahashi¹ (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ., 2.Dept. of Biol. Sci. Grad. Sch. of life Sci., Hokkaido Univ., 3.Div. of Microbial Genetics, Nat. Inst. of Genetics, 4.SOKENDAI)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0152] Function of chromatin remodeler associated with the induction of mismatch repair-dependent apoptosis.

〇Yukimasa Takeishi¹, Ryosuke Fujikane², Tatsuro Takahashi³, Mutsuo Sekiguchi¹, Masumi Hidaka² (1.Adv. Sci. Res. Center, Fukuoka Dental Col., 2.Dep. of Physiol. Sci. and Mol. Biol., Fukuoka Dental Col., 3.Dept. of Biol. Sci., Grad. Sch. of Sci., Osaka Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0153] Propagation of Sox-Oct motif-dependent DNA demethylation on chromosome is necessary for the formation and maintenance of widespread hypomethylation at H19-ICR

〇Shuichi Kubo¹, Naohiro Hori¹, Kiyotaka Hatsuzawa¹ (1.Div. of Molec. Biol., Fac of Med., Tottori Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0154] DNA Methylation-Dependent and -Independent Regulation of Monoallelic Expression by Zfp57 in Ground-State Embryonic Stem Cells

〇Hiroaki Ohishi¹, Motoko Unoki¹, Kenji Ichiyanagi², Kei Fukuda³, Shoji Maenohara¹, Hatsune Chiba⁴, Takashi Sado⁵, Hiroyuki Sasaki¹ (1.Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University, 2.Division of Genome and Epigenome Dynamics, Graduate School of Agriculture, Nagoya University, 3.Cellular Memory Laboratory, RIKEN, 4.Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine, 5.Laboratory for Epigenetics and Development, Department of Advanced Bioscience, Graduate School of Agriculture, Kindai University)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0155] Identification of regulatory elements responsible for allele-specific DNA methylation of the mouse H19 ICR

〇Hitomi Matsuzaki^1,2, Daichi Kuramochi³, Aki Ushiki³, Keiji Tanimoto^1,2 (1.Faculty of Life and Environmental Sci., Univ. of Tsukuba, 2.TARA Center, Univ. of Tsukuba, 3.Grad. Sch. of Life and Environmental Sci., Univ. of Tsukuba)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0156] NSD1 haploinsufficiency evokes DNA hypomethylation at imprinted DMRs and the increased expression of imprinted genes.

〇Hidetaka Watanabe¹, Ken Higasimoto¹, Noriko Miyake², Toshiyuki Maeda¹, Hidenori Hidaka¹, Saori Aoki¹, Hitomi Yatsuki¹, Kenichi Nishioka¹, Keiichiro Jyo¹, Sumiyo Morita³, Takuro Horii³, Mika Kimura³, Izuho Hatada³, Naomichi Matsumoto², Hidenobu Soejima¹ (1.Division of Molecular Genetics & Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 2.Yokohama City University, Graduate School of Medicine, Department of Human Genetics, 3.Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0157] Functional analysis of a maternally methylated DMR on mouse Dlk1-Dio3 domain

〇Satoshi Hara¹, Takeshi Saito¹, Shuji Takada¹ (1.Dept. of Systems BioMed, NRICHD)

The 39th Annual Meeting of the Molecular Biology Society of Japan