[1P-0525] Deficiency of AMPA receptor-palmitoylation aggravates the seizure susceptibility

〇Masayuki Itoh¹, Mariko Yamashita², Masaki Kaneko¹, Hiroyuki Okuno^3,4, Manabu Abe⁵, Maya Yamazaki⁵, Rie Natsume⁵, Daisuke Yamada⁶, Toshie Kaizuka¹, Reiko Suwa¹, Kenji Sakimura⁵, Masayuki Sekiguchi⁶, Keiji Wada⁶, Mikio Hoshino², Masayoshi Mishina^7,8, Takashi Hayashi^1,7 (1.Sect of Cell Biochem, Dept of Biochem and Cell Biol, NIN, NCNP, 2.Dept of Biochem and Cell Biol, NIN, NCNP, 3.MIC/SK Proj, Grad Sch of Med, Kyoto Univ, 4.Dept of Biochem and Mol Biol, Grad Sch of Med and Dent Sci, Kagoshima Univ, 5.Dept of Cell Neurobiol, Brain Res Inst, Niigata Univ, 6.Dept of Degenerative Neurol Dis, NIN, NCNP, 7.Dept of Mol Neurobiol and Pharmacol, Grad Sch of Med, Univ of Tokyo, 8.Brain Sci Lab, Res Org of Sci and Tech, Ritsumeikan Univ)

AMPA receptor, palmitoylation, epileptic seizure