The Molecular Biology Society of Japan

[1P-0526] Neural stem cell-specific Itpa knockout mouse as a model of human epileptic encephalopathy caused by ITPA deficiency

〇Daisuke Tsuchimoto1, Yuichiro Koga1, Yoshinori Hayashi2, Nona Abolhassani1, Yasuto Yoneshima1, Hiroshi Nakanishi3, Yusaku Nakabeppu1 (1.Div.Neurofunc.Genomics, Med.Ins.Bioreg., Kyushu Univ., 2.Dep. Aging Sci. Pharm, Fac. Dent. Sci., Kyushu Univ., 3.Dep Pharm., Fac Pharm, Yasuda Women’s Univ.)

ITPA, Inosine triphosphate, Epilepsy, Resting membrane potential, Depolarization

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