[1P-0687] Gene therapy using Adeno-Associated Virus Vectors in a Plp1-transgenic mouse model of Pelizaeus-Merzbacher disease

〇Heng Li¹, Hironori Okada², Kazuhisa Sakai³, Takashi Okada², Noritaka Ichinohe³, Yu-ichi Goto¹, Ken Inoue¹ (1.Dept of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 2.Dept of Molecular and Medical Genetics, Graduate School of Medicine, Nippon Medical School, 3.Dept of Ultrastructural Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry)

inherited hypomyelinaitng leukodystrophy, gene therapy, Adeno-associated virus, artificial miRNA