[1P-0723] Large fragment knock-in by zygote genome editing with adeno-associated viral vector and CRISPR/Cas9.

〇Naoaki Mizuno¹, Eiji Mizutani¹, Hideyuki Sato¹, Mariko Kasai¹, Tomoyuki Yamaguchi¹, Hiromitsu Nakauchi^1,2 (1.Div. of Stem Cell Therapy, IMSUT, University of Tokyo., 2.Inst for Stem Cell Biol and Reg Med, Stanford University.)

genome editing, large fragment knock-in, transgenic animal, zygote genome editing