The Molecular Biology Society of Japan

[1P-0774] Inverse agonism of compounds with benzamidine moiety at GPCR activity

〇Tetsuya Hori1,2, Toshiaki Okuno3, Asuka Inoue4, Takamitsu Hosoya2, Junken Aoki4, Takehiko Yokomizo3, Shigeyuki Yokoyama1 (1.RIKEN Yokoyama Lab., 2. Laboratory for Chemical Biology, RIKEN BDR, 3.Dept. of Biochem., Juntendo Univ. School of Med., 4.Grad. Sch. of Pharm. Sci., Tohoku Univ)

GPCR, Inverse agonist, Rational design, Structure, Benzamidine moiety

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