5:47 PM - 6:01 PM

[1PW2-13-2] O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking

〇Hideyuki Takeuchi¹, Hongjun Yu², Huilin Hao³, Megumi Takeuchi³, Atsuko Ito³, Tetsuya Okajima¹, Huilin Li², Robert S. Haltiwanger³ (1.Dept of Mol Biochem, Nagoya Univ Grad Sch of Med, 2.Van Andel Res Institute, 3.CCRC, Univ of Georgia)

Notch signaling, O-glucose, protein O-glucosyltransferase, EGF repeats, protein stability