The Molecular Biology Society of Japan

[2P-0132(1PW1-03-3)] Z4 co-regulator dependent-survival of NUT Carcinoma through hiperacetylated megadomain formation

〇Hitoshi Shiota1, Janine E. Elya1, Artyom A. Alekseyenko2, Paulin M. Chou3, Shelby A. Gorman4, Olena Barbash4, Kelly Becht1, Kristina Danga1, Mitzi I. Kuroda2, Valentina Nardi5, Christopher A. French1 (1.Dept. Pathology, Brigham and Women's Hospital/Harvard Medical School, 2.Division of Genetics, Dept. Medicine, Brigham and Women's Hospital/Harvard Medical School, 3.Dept. Pathology, Ann and Robert H. Lurie Children's Hospital of Chicago, 4.Cancer Epigenetics DPU, Oncology R&D, GSK, 5.Dept. Pathology, Massachusettes General Hospital/ Harvard Medical School)

NMC, BRD4-NUT, Megadomain, ZNF532, ZNF592

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