Identification of the synthetic lethal gene under the condition of PARG dysfunction and analysis of cell death mechanisms

Yuka Sasaki; Hiroaki Fujimori; Miyuki Hozumi; Takae Onodera; Yasufumi Murakami; Fumiaki Koizumi; Kengo Inoue; Mitsuko Masutani

[2P-0611(2AW-09-1)] Identification of the synthetic lethal gene under the condition of PARG dysfunction and analysis of cell death mechanisms

〇Yuka Sasaki^1,2, Hiroaki Fujimori³, Miyuki Hozumi^3,4, Takae Onodera^1,2, Yasufumi Murakami⁴, Fumiaki Koizumi^5,1, Kengo Inoue⁶, Mitsuko Masutani^1,2 (1.Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Lab of Collaborative Research, Div. Cell Signaling, Natl. Cancer Ctr. Res. Inst., 3.Div. Chemother. and Clin. Res., Natl. Cancer Ctr. Res. Inst., 4.Tokyo Univ. Sci., Fac. Indus. Sci. Tech., 5.Div. Clin. Res. Support, Komagome Hosp., 6.Pharma Valley Center)

poly(ADP-ribosyl)ation, PARG, synthesic lehtality, poly (ADP-ribose), anti-cancer agent

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The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0611(2AW-09-1)] Identification of the synthetic lethal gene under the condition of PARG dysfunction and analysis of cell death mechanisms

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