[2P-0734] Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery

〇Aki Tanabe⁷, Kazumi Nakano⁴, Makoto Nakakido^1,2, Satoru Nagatoisi³, Yuetsu Tanaka⁶, Kouhei Tsumoto^1,2,3, Kaoru Uchimaru⁴, Toshiki Watanabe⁵ (1.Dept. of Bioeng., Sch. of Eng,. Univ. of Tokyo, 2.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 3.Inst. of Med. Sci., Univ. of Tokyo, 4.Dept of Computational Biology and Medical Sciences, Graduate Sch. of Frontier Sci., Univ of Tokyo, 5.IMSUT Hospital, Univ. of Tokyo, 6.Dept of Immunology, Graduate School of Medicine, Univ of the Ryukyus, 7.Sch. of Eng,. Univ. of Tokyo)

single-chain variable fragment, OX40, antibody engineering, Drug delivery, Internalization