[3P-0060] Kinetics studies on GTP hydrolysis process of oncogene product Ras based on the structural changes using photo-controllable caged-GTP.

〇Chika Hagihara¹, Yoshiteru Makino¹, Shigeyuki Matsumoto², Takashi Kawamura³, Ichiro Mori¹, Eriko Nango⁴, Takashi Kumasaka³, Fumi Shima¹ (1.Graduate School of Science, Technology and innovation, Kobe University, 2.Graduate School of medicine, Kobe University, 3.Japan Synchrotron Radiation Research Institute, 4.RIKEN Spring-8 center)

proto-oncogenes products Ras, hydrolysis reaction rate, X-ray crystal structure analysis, nuclear magnetic resonance spectrometry , Structural changes