The Molecular Biology Society of Japan

[3P-0060] Kinetics studies on GTP hydrolysis process of oncogene product Ras based on the structural changes using photo-controllable caged-GTP.

〇Chika Hagihara1, Yoshiteru Makino1, Shigeyuki Matsumoto2, Takashi Kawamura3, Ichiro Mori1, Eriko Nango4, Takashi Kumasaka3, Fumi Shima1 (1.Graduate School of Science, Technology and innovation, Kobe University, 2.Graduate School of medicine, Kobe University, 3.Japan Synchrotron Radiation Research Institute, 4.RIKEN Spring-8 center)

proto-oncogenes products Ras, hydrolysis reaction rate, X-ray crystal structure analysis, nuclear magnetic resonance spectrometry , Structural changes

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