[3P-0125] Ryuvidine inhibits JARID1A demethylase and reduces survival of drug-tolerant cancer cells

〇Shogo Yoshida¹, kazuki Katayama¹, Eishin Mitsui¹, Mie Tsuchida¹, Shuichi Wada¹, Makoto Hasegawa¹, Ryuzo Sasaki¹, Tamio Mizukami¹, Akihiro Ito^2,3, Koshiki Mino⁴, Tetsuo Onuki⁴, Minoru Yoshida^3,4,5 (1.Nagahama Institute of Bio-Science and Technology, 2.Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 3.Chem. Genomics, RIKEN CSRS, 4.Drug Discov. Seed Cpds. Explorat. Unit, RIKEN CSRS, 5.Dept. of Biotechnol.,The Univ. of Tokyo)

Histone demethylase, JARID1A, epigenetics