4:02 PM - 4:16 PM

[3PW-12-2] Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment

〇Ayami Okuzumi¹, Masaru Kurosawa², Taku Hatano¹, Tomoyuki Yamanaka³, Haruko Miyazaki³, Yoshiaki Furukawa⁴, Nobutaka Hattori¹, Nobuyuki Nukina³ (1.Depart of Neurol, Juntendo Univ Sch of Med, 2.Inst for Environmental & Gender-specific Medicine, Juntendo grad Sch of Med, 3.Lab of Structural Neuropathol, Doshisha Univ Grad Sch of Brain Sci, 4.Lab for Mechanistic Chem of Biomolecules, Dept of Chem, Keio Univ)

Rapid dissemination, alpha-synuclein, propagation, callosotomy