The Molecular Biology Society of Japan

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[3PW-12-2] Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment

〇Ayami Okuzumi1, Masaru Kurosawa2, Taku Hatano1, Tomoyuki Yamanaka3, Haruko Miyazaki3, Yoshiaki Furukawa4, Nobutaka Hattori1, Nobuyuki Nukina3 (1.Depart of Neurol, Juntendo Univ Sch of Med, 2.Inst for Environmental & Gender-specific Medicine, Juntendo grad Sch of Med, 3.Lab of Structural Neuropathol, Doshisha Univ Grad Sch of Brain Sci, 4.Lab for Mechanistic Chem of Biomolecules, Dept of Chem, Keio Univ)

Rapid dissemination, alpha-synuclein, propagation, callosotomy

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