4:56 PM - 5:13 PM

[3PW-16-5] Decoding global transcriptome dynamics of genome encoded polyadenylation and autoregulation with novel small-molecule modulators of alternative polyadenylation

〇Shinsuke Araki¹, Yusuke Nakayama¹, Osamu Sano¹, Shoichi Nakao¹, Mari Shimizu Ogasawara¹, Hiroyoshi Toyoshiba¹, Atsushi Nakanishi¹, Samuel Aparicio^2,3 (1.Research, Takeda Pharmaceutical Co. Ltd., 2.Mol Oncology, BC Cancer Agency, 3.Dept of Pathol and Lab Medicine, Univ of British Columbia)

Alternative polyadenylation, PABPN1, Reporter screening, RNA binding protein, Alternative splicing