[2P-0451] Molecular role of Geminin in the regulatory system of cell cycle and differentia
tion in hematopoietic stem cells

〇Kyoko Takedachi¹, Yoshinori Ohno¹, Naoto Shirasu², Motoaki Ohtsubo³, Shin'ichiro Yasunaga², Yoshihiro Takihara⁴ (1.Dept. Stem Cell Biol., RIRBM, Hiroshima Univ, 2.Dept. Biochem., Facul. Med., Fukuoka Univ., 3.Dept. Food and Ferment. Sci., Beppu Univ., 4.Japanese Red Cross Osaka Blood Center.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0452] Molecular responses for low dose-rate irradiation in the hematopoiesis

〇Yoshinori Ohno¹, Kyoko Takedachi¹, Yun Guo², Masamoto Kanno², Naoto Shirasu³, Shin’ichiro Yasunaga³, Motoaki Ohtsubo⁴, Yoshihiro Takihara^1,5 (1.Dept. Stem Cell Biol., RIRBM, Hiroshima Univ., 2.Dept. Immunol., Grad. Sch. Biomed. Sci., Hiroshima Univ., 3.Dept. Biochem., Facul. Med., Fukuoka Univ., 4.Dept. Food and Ferment. Sci., Beppu Univ., 5.Japanese Red Cross Osaka Blood Center.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0453(1PW1-04-4)] Rap1 GTPase regulates Notch-dependent hematopoietic stem cell development by promoting integrin-mediated cell adhesion

〇Rho Seung-Sik¹, Isao Kobayashi², Koji Ando³, Eri Oguri-Nakamura¹, Hiromi Hirata⁴, Atsuo Iida⁵, Naoki Mochizuki³, Shigetomo Fukuhara¹ (1.Nippon Medical School, 2.Kanazawa University, 3.National Cerebral and Cardiovascular Center Research Institute, 4.Aoyama Gakuin University, 5.Kyoto University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0454] Functional study of cytokines on self-renewal and differentiation of hematopoietic stem cell

〇Chihiro Kodama¹, Yijun Tian², Yukine Kato², Kayano Toume¹, Kenkichi Sugimoto² (1.Department of Biology Faculty of Science, Niigata Univ., 2.Graduate school of science and technology, Niigata Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0455] Ca²⁺-mitochondria pathway regulates cell division in hematopoietic stem cells

〇Terumasa Umemoto¹, Michihiro Hashimoto¹, Toshio Suda^1,2 (1.International Research Center for Medical Sciences, Kumamoto University, 2.Cancer Science Institute, National University of Singapore)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0456] CCL5/RANTES specifically restricts the proliferation of leukemic stem cells in a hematopoietic niche model

〇Chie Goto¹, Aya Yokoi¹, Kana Kuronuma¹, Naoko Okada¹, Mirano Kajitani¹, Leo Matsubara¹, Natsumi Hasegawa¹, Shigetaka Asano², Mitsuhiro Ito^1,2 (1.Div. of Med. Biophysics, Grad. Sch. of Health Sci., Kobe Univ., 2.Res. Org. for Nano & Life Innov., Waseda Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0457] Autism-related gene CHD8 contributes to differentiation of hematopoietic stem cells

〇Akihiro Nita¹, Yoshiharu Muto¹, Yuta Katayama¹, Akinobu Matsumoto¹, Masaaki Nishiyama², Keiichi I Nakayama¹ (1.Dept. Mol. Cell. Biol., Med. Inst. Bioreg., Kyushu Univ., 2.Dept. Histol. Cell Biol., Grad. Sch. Med. Sci., Kanazawa Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0458] Generation of reconstituted hemato-lymphoid murine embryo by intra-placental injection

〇Hyojung Jeon¹, Keigo Asano¹, Tomomasa Yokomizo², Michito Hamada¹, Satoru Takahashi¹ (1.Dept. of Anatomy and Embryology, Fac. of Medicine, Univ. of Tsukuba, 2.IRCMS, Kumamoto Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0459] The role of an epigenetic factor TET1 in undifferentiated hematopoietic cell clusters in the embryonic AGM region where definitive hematopoiesis arises

〇Koya Azuma¹, Ikuo Nobuhisa¹, Kiyoka Saito¹, Naoki Iizuka¹, Tetsuya Taga¹ (1.Dept of Stem Cell Regulation, Medical Research Institute, Tokyo Medical and Dental Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0460] Involvement of an NF-κB signal pathway in the maintenance of an undifferentiated state of hematopoietic stem cell-containing clusters in the midgestation mouse dorsal aorta

〇Naoki Iizuka¹, Ikuo Nobuhisa¹, Kiyoka Saito¹, Koya Azuma¹, Tetsuya Taga¹ (1.Dept of Stem Cell Regulation, Medical Research Institue, Tokyo Medical and Dental Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan