[1PW1-13-5] More than Just an Immunosuppressant: The Emerging Role of FTY720 as a Novel Inducer of Apoptosis via ROS and Iron Regulation

〇Reiko Sugiura¹ (1.Dept of Pharm Sci, Kindai Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:46 PM - 4:59 PM

[1PW1-13-6] Development of ferroptosis-inducing cancer therapy using xCT inhibitor and the drug screening to overcome cancer cell resistance to xCT inhibition

〇Osamu Nagano¹ (1.Div. of Gene Regulation, IAMR, Keio Univ. Sch. of Med. )

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:59 PM - 5:15 PM

[1PW1-14-1] Roles of mitochondrial respiratory supercomplex in endometrial cancer and application of patient-derived model

〇Kazuhiro Ikeda¹, Kuniko Horie¹, Satoshi Inoue^1,2 (1.Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University , 2.Systems Aging Science and Medicine, Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 3:45 PM - 3:57 PM

[1PW1-14-2(2P-0092)] MCM10 maintains breast cancer stem-like cells through encouraging rapid response to replication stress

〇Takahiko Murayama¹, Tatsunori Nishimura², Masao Yano³, Asako Sasahara⁴, Kei-ichiro Tada⁴, Arinobu Tojo¹, Noriko Gotoh² (1.Div. Mol. Therapy, IMS, Univ. Tokyo, 2.Div. Cancer Cell Biol., Cancer Res. Inst. Kanazawa Univ, 3.Dept. Surg., Minamimachida Hosp, 4.Dept. Breast & Endocrine Surg., Grad. Sch. Med., Univ. Tokyo)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 3:57 PM - 4:09 PM

[1PW1-14-3(3P-0785)] Elucidation of immunosuppressive mechanism by visualization of HIF activity of tumor stromal cells by highly sensitive luminescence imaging

〇Ryuichiro Hirano¹, Hitomi Miyabara¹, Tetsuya Kadonosono¹, Takahiro Kuchimaru², Hitomi Watanabe³, Gen Kondoh³, Shinae Kondoh¹ (1.School of Life Science and Technology, Tokyo Institute of Technology, 2.Jichi Medical University, Center for Molecular Medicine, 3.Kyoto University, Institute for Frontier Life and Medical Sciences, Laboratory of Integrative Biological Science)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:09 PM - 4:18 PM

[1PW1-14-4] Integrative genomic analysis of androgen receptor target signals identified a new mechanism by COBLL1 for prostate cancer progression

〇Ken-ichi Takayama¹, Satoshi Inoue¹ (1. Department of Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:18 PM - 4:30 PM

[1PW1-14-5] Analysis of regulatory mechanisms in breast cancer-stem like cells by using spheroid cultures and PDX models

〇Noriko Gotoh¹ (1.Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:30 PM - 4:42 PM

[1PW1-14-6] Elucidation of cancer heterogeneity using three-dimensional culture and PDX models

〇Koji Okamoto¹ (1.Natl. Cancer Center Res. Inst.)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:42 PM - 4:54 PM

[1PW1-14-7(2P-0634)] A whole animal platform to advance a clinical kinase inhibitor into new disease space

〇MASAHIRO SONOSHITA^1,2, Ross Cagan², Arvin Dar³ (1.Div of Biomed Oncol, Inst for Genet Med, Hokkaido Univ, 2.Dept of Dev & Regen Biol, Icahn Sch of Med at Mount Sinai, 3.Dept of Oncol Sci, Icahn Sch of Med at Mount Sinai)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 4:54 PM - 5:03 PM

[1PW1-14-8] Epigenetic regulators Bmi1 and Sox2 in therapeutic resistance to anti-androgen therapy

〇Sarki A Abdulkadir¹, Young A Yoo¹ (1.Dept of Urology and Pathology, Northwestern University Chicago)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Wed. Nov 28, 2018 5:03 PM - 5:15 PM