[3P-0468] Dendritic localization of mRNAs for Arf GEFs and GAPs involved in spine formation in dendrites

〇Rie Ohashi^1,2, Yoshitaka Kimori³, Nobuyuki Shiina^1,2,4 (1.Lab. of Neuronal Cell Biol., National Inst. for Basic Biol., 2.Dep. of Basic Biol., SOKENDAI, 3.Dep. of Mgmt. and Info. Sci., Faculty of Environ. and Info. Sci., Fukui Univ. of Tech., 4.Exp. Res. Ctr. on Life and Living Syst., National Inst. for Nat. Sci.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0469] Identification of factors modulating the clearance of aggregated tau through genome-wide siRNA screening and CRISPR screening

〇Shinpei Ao¹, Kazuki Ohtake¹, Yasuyuki Sakurai¹, Shoshiro Hirayama¹, Shigeo Murata¹ (1.Dept of Pharmacy, Univ of Tokyo)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0470(3AW-12-2)] The impact of non-coding variants associated with Alzheimer’s disease via chromatin higher-order structure

〇Masataka Kikuchi¹, Norikazu Hara², Mai Hasegawa¹, Akinori Miyashita², Ryozo Kuwano³, Takeshi Ikeuchi², Akihiro Nakaya¹ (1.Dept of Med, Univ of Osaka, 2.Brain Res Inst, Univ of Niigata, 3.Asahigawasou Res Inst)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0471] Visualization of pathological effects of amyloid beta on movements of glutamate receptors

〇Tanaka Hiromitsu¹, Sakaguchi Daiki¹, Hirano Tomoo¹ (1.Department of Biophysics, Graduate School of Science, Kyoto University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0472] Analysis of fetal growth defects and expression of extracellular matrix in β-secretase deficient mice

〇Yoshihiro Nishida¹, Hiroyuki Yano², Miki Ohta³, Hirokazu Kitamura⁴, Hisashi Narahara¹, Toshikatsu Hanada³, Ryouji Hamanaka⁵ (1.Faculty of Medicine, Dept of Obstet and Gynecol, Oita University, 2.Institute of Sci Res, Div of RI Res, Oita University, 3.Faculty of Medicine, Cel Biol, Oita University, 4.Faculty of Medicine, Matrix Med, Oita University, 5.Dept of Health Sci, Human Biol, Oita Univ of Nursing and Health Sci)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0473] Amyloid beta aggregates interact with NLRP3 resulting in the initiation of inflammasome activation

〇ayaka Nakanishi¹, Naoe Kaneko^2,3, Tamotsu Zako¹, Jyunya Masumoto^2,3 (1.Department of Chemistry and Biology, Ehime University Graduate School of Science and engineering, 2.Department of Pathology, Ehime University Graduate School of Medicine, 3.Department of Pathology, Ehime University Proteo-Science Center)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0474] Study on biomarkers for diagnosis of rapidly progressive dementias

〇Yusuke Sanuki¹, Ryo Ezaki¹, Syuichi Hurusawa¹, Noriyuki Nishida², Katsuya Satoh², Hiroyuki Horiuchi¹ (1.Lab of Immunobio, Graduate School of Biosphere Sci, Academy Biol and Life Sci, Univ of Hiroshima, 2.Dept of Molecular Microbiology and Immunology, Graduate School of Biomedical Sci, Univ of Nagasaki)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0475] Identification and mechanisms of neuron-protective compounds in plant extract

〇Ayako Tanaka¹, Nozomi Tagai¹, Akira Sato¹, Fumiaki Uchiumi¹, Sei-ichi Tanuma² (1.Facul. Pharm. Sci., Tokyo Univ. Sci., 2.Res. Inst. Sci. & Tech., Org. Res. Adv., Tokyo Univ. Sci)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0476] Study of suppressive mechanism of curcumin derivative GT863 for Aβ production

〇Mina Takahachi¹, Yasuomi Urano¹, Hachiro Sugimoto², Noriko Noguchi¹ (1.Sys. Life Sci. Lab., Grad. Sch. of Life & Med. Sci., Doshisha Univ., 2.Grad. Sch. of Life & Med. Sci., Doshisha Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0477] Molecular commonalities between auditory hair cells and neurons in the study of age-related neuronal disorder

〇Ryunosuke Minami¹, Young-Mi Lim¹, Leo Tsuda¹ (1.Laboratory of Animal Models of Aging, National Center for Geriatrics and Gerontology)

The 41st Annual Meeting of the Molecular Biology Society of Japan