[3PW-13-2] Molecular pathogenesis of Cockayne syndrome and ubiquitination of RNA polymerase in transcription coupled nucleotide excision repair

Chaowan Guo¹, Nan Jia¹, Yasuyoshi Oka¹, Yuka Nakazawa¹, 〇Tomoo Ogi¹ (1.Dept of Genetics, RIeM, Nagoya Univ / Dept of Human Genetics, Grad Sch of Med, Nagoya Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:01 PM - 4:13 PM

[3PW-13-3] The mechanism by which the microRNA biogenesis protein, DGCR8, regulates transcription-coupled nucleotide excision repair

〇Toshiyasu Taniguchi¹, Takaaki Watanabe¹ (1.Department of Molecular Life Science, Tokai University School of Medicine)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:13 PM - 4:25 PM

[3PW-13-4(2P-0106)] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair

〇Reona kato¹, Takaaki Yasuhara¹, Yoshihiko Hagiwara², Bunsyo Shiotani³, Motohiro Yamauchi⁴, Shinichiro Nakada⁵, Atsushi Shibata², Kiyoshi Miyagawa¹ (1.Laboratory of Molecular Radiology, The University of Tokyo, 2.Education and Research Support Center, Gunma University, 3.Division of Cellular Signaling, National Cancer Center Research Institute, 4.Division of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki University,, 5.Department of Bioregulation and Cellular Response, Graduate School of Medicine, Osaka University)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:25 PM - 4:37 PM

[3PW-13-5] Regulation of the endonuclease scaffold protein SLX4 via ubiquitination pathway

〇Yoko Katsuki¹, Masako Abe¹, Haico van Attikum², Shinichiro Nakada³, Masato Kanemaki⁴, Yonghwan Kim⁵, Miharu Yabe⁶, Hiromasa Yabe⁶, Minoru Takata¹ (1.Radiat Biol Center, Grad Sch of Biostu, Kyoto Univ, 2.Med Center, Leidan Univ, 3.Dept of Bioreg & Cell Resp, Grad Sch of Med, Osaka Univ, 4.Div of Mol Cell Eng, Nat Inst of Genet, 5.Genome Maint, Sookmyung Women's Univ, 6.Dept of Cell Transplant & Regene Med, Tokai Univ Sch of Med)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:37 PM - 4:49 PM

[3PW-13-6(2P-0089)] Intrinsic DNA Replication Stress Provides an Indication of Sensitivity to ATR inhibitor in Lung Adenocarcinoma Cell

〇Kiminori kurashima¹, Hideto Kashiwagi¹, Takashi Kohno², Bunsyo Shiotani¹ (1.Div. Cellular Signaling, Natl. Cancer Car. Res. Inst., 2.Div. Genome Biology, Natl. Cancer Car. Res. Inst.)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:49 PM - 5:01 PM

[3PW-13-7] BRCA1 ensures genome integrity by eliminating estrogen-induced pathological Topoisomerase II-DNA complexes

〇Hiroyuki Sasanuma¹, Masataka Tsuda^1,6, Suguru Morimoto¹, Junji Itou³, Masakazu Toi³, Shinichiro Nakada⁵, Ken Tsutsui⁴, Andre Nussenzweig², Takeda Shunichi¹ (1.Department of radiation genetics, Graduate school of medicine, Kyoto university, 2.NIH, 3.Department of breast surgery, Graduate school of medicine, Kyoto university, 4.Graduate School of Medicine, Okayama university, 5.Department of Bioregulation and Cellular Response, Institute for Advanced Co-Creation Studies, Osaka University, 6.Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 5:01 PM - 5:13 PM

[3PW-14-1] Growing understandings of development of trisomy with advancing maternal age

〇Makiko Tsutsumi¹, Hiroki Kurahashi¹ (1.Div of Mol Genet, ICMS, Fujita Health Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 3:47 PM - 4:04 PM

[3PW-14-2] Spatial organization of chromosome territories (CTs) and its characteristics in the chromosome 21-trisomic cell nucleus

〇Hideyuki Tanabe¹ (1.Dept. of ESB, Sch. of Advanced Sci., SOKENDAI (The Graduate Univ. for Advanced Studies))

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:04 PM - 4:21 PM

[3PW-14-3] Analysis of vascular homeostasis regulation system by mouse model of Down’s syndrome

〇Masashi Muramatsu¹, Akiya Akahoshi¹, Yuuri Miyamura¹, Tsuyoshi Osawa², Suguru Nakagawa³, Takashi Minami¹ (1.Divi. of Mol and Vas Biol, IRDA, Kumamoto Univ, 2.Int Nutrio and Oncol, RCAST, the Univ of Tokyo, 3.Dept. of Oph, Graduate School of Medicine, the Univ of Tokyo)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:21 PM - 4:38 PM

[3PW-14-4(3P-0496)] Triplicated responsible gene for an abnormal number of inflammatory cells and impaired cortical neurogenesis in the embryonic brain of a Down syndrome model mouse

〇Keiichi Ishihara¹, Ryohei Shiimizu¹, Eri Kawashita¹, Warren S. Alexander², Haruhiko Sago³, Kazuhiro Yamakawa⁴, Satoshi Akiba¹ (1.Depart of Pathol Biochem, Kyoto Pharm Univ, 2.Cancer and Haematol Div, The Walter and Eliza Hall Inst of Med Res, 3.Div of Fetal Med, Natl Ctr for Child Health & Dev, 4.Lab for Neurogenet, RIKEN)

The 41st Annual Meeting of the Molecular Biology Society of Japan |Fri. Nov 30, 2018 4:38 PM - 4:55 PM