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[1AW-06-7(1P-0440)] IL-6 induced by IL-17A produced from γδT cells plays a critical role in mortality and vascular leakage of severe dengue hemorrhagic fever in mice

〇Takeshi Kurosu1, Daisuke Okuzaki2, Supranee Phanthanawiboon3, Tomoki Yoshikawa1, Masayuki Shimojima1, Masaaki Murakami4, Daisuke Kamimura4, Noriyo Nagata5, Naoko Iwata5, Masayuki Saijo1 (1.Department of Virology I, National Institue of Infectious Diseases, 2.Research Institute for Microbial Diseases, 3.Department of Microbiology, Faculty of Medicine, Khon Kaen University, 4.Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, 5.Department of Pathology, National Institue of Infectious Diseases)

viral hemorrhagic fever, dengue virus, vascular leakage, mouse model

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