The Molecular Biology Society of Japan

[1LBA-017] Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

〇Yumiko Tahira1,2, Wenyu Miao1, Katsuya Sakai1,2, Hiroki Sato 2, Ryu Imamura1,2, Nawaphat Jangphattananont1, Kunio Matsumoto1,2,3 (1.Div. of Tumor Dynamics & Regulation, Cancer Research Inst., Univ. of Kanazawa, 2.Nano Life Science Inst. (WPI-NanoLSI), Univ of Kanazawa, 3.Inst. for Frontier Science Initiative, Univ. of Kanazawa)

MET receptor, affinity, hepatocyte growth factor, loss of function, missense mutation

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