The Molecular Biology Society of Japan

[1P-0127] ATRA dependent interaction of MED1 with oncofusion protein PML-RARα initiates transcriptional activation

〇Tomoya Fukuoka1, Miki Matsuo1, Hikaru Tsutsumi1, Rino Kishida1, Manami Tsuji1, Mana Morikawa1, Mizuha Anamoto1, Naoya Kanada1, Kyo Saiki1, Roeder G. Robert2, Natsumi Hasegawa1, Mitsuhiro Ito1,2 (1.Div. Med. Biophysics, Kobe Univ. Grad. Sch. Health Sci., 2.Biochem. & Mol. Biol., The Rockefeller Univ.)

PML-RARα, transcriptional activation, Mediator, MED1, LxxLL nuclear receptor recognition motifs

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