IL-6 induced by IL-17A produced from &#947;&#948;T cells plays a critical role in mortality and vascular leakage of severe dengue hemorrhagic fever in mice

Takeshi Kurosu; Daisuke Okuzaki; Supranee  Phanthanawiboon; Tomoki Yoshikawa; Masayuki Shimojima; Masaaki Murakami; Daisuke Kamimura; Noriyo Nagata; Naoko Iwata; Masayuki Saijo

[1P-0440(1AW-06-7)] IL-6 induced by IL-17A produced from γδT cells plays a critical role in mortality and vascular leakage of severe dengue hemorrhagic fever in mice

〇Takeshi Kurosu¹, Daisuke Okuzaki², Supranee Phanthanawiboon³, Tomoki Yoshikawa¹, Masayuki Shimojima¹, Masaaki Murakami⁴, Daisuke Kamimura⁴, Noriyo Nagata⁵, Naoko Iwata⁵, Masayuki Saijo¹ (1.Department of Virology I, National Institue of Infectious Diseases, 2.Research Institute for Microbial Diseases, 3.Department of Microbiology, Faculty of Medicine, Khon Kaen University, 4.Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, 5.Department of Pathology, National Institue of Infectious Diseases)

viral hemorrhagic fever, dengue virus, vascular leakage, mouse model

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The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0440(1AW-06-7)] IL-6 induced by IL-17A produced from γδT cells plays a critical role in mortality and vascular leakage of severe dengue hemorrhagic fever in mice

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