In vitro selection and affinity maturation of CTLA-4 binding cyclic peptide with PURE<I>frexRD</I>, and conversion of the peptide to small molecules.

Kanehisa Kojoh; Kumiko Tsuihiji; Shizue Katoh; Mikiko Nakamura; Satoshi Murakami; Hajime Takashima; Masaji Kasai; Mutsumi Mouri; Atsushi Yoshimori

[1P-0603] In vitro selection and affinity maturation of CTLA-4 binding cyclic peptide with PUREfrexRD, and conversion of the peptide to small molecules.

〇Kanehisa Kojoh¹, Kumiko Tsuihiji¹, Shizue Katoh¹, Mikiko Nakamura¹, Satoshi Murakami¹, Hajime Takashima², Masaji Kasai², Mutsumi Mouri², Atsushi Yoshimori³ (1.GeneFrontier.Co, 2.PRISM BioLab.Co, 3.Institute for Theoretical Medicine, Inc.)

Cyclic Peptide, Ribosome Display, CTLA-4

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The 42nd Annual Meeting of the Molecular Biology Society of Japan

[1P-0603] In vitro selection and affinity maturation of CTLA-4 binding cyclic peptide with PUREfrexRD, and conversion of the peptide to small molecules.

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