The Molecular Biology Society of Japan

[1P-0616] Transplacental delivery of CRISPR components via tail vein of pregnant female causes mutations in embryonic cardiomyocytes of murine fetuse

〇Shingo Nakamura1, Naoko Ando1, Satoshi Watanabe2, Masayuki Ishihara1, Masahiro Sato3 (1.Div.Biomed.Eng., Natl.Def.Med.Coll.Res.Inst., 2.Anim.Genome, Div.Anim.Breed.Res., NILGS, 3.Sect.Gene.Exp.Reg., Front.Sci.Res.Ctr., Kagoshima Univ.)

CRISPR/Cas9, fetuses, genome editing, transplacental gene delivery

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