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[1PW-04-2] Novel role of TDP-43 as an RNA chaperone to suppress neurodegeneration via regulation of UGGAA repeat RNA aggregation and repeat-associated translation

〇Yoshitaka Nagai1, Kinya Ishikawa2 (1.Dept. of Neurotherapeutics, Grad. Sch. of Med., Osaka Univ., 2.Dept. of Personalized Genomic Med. for Health, Grad. Sch., Tokyo Med. Dent. Univ.)

神経変性疾患, ノンコーディングリピート病, RNAシャペロン, リピート関連ATG非依存性翻訳, TDP-43

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