10:16 AM - 10:37 AM

[2AW-07-5] Patients with a gene encoding a truncated ADP-ribosyl-acceptor hydrolase 3 exhibit a progressive neurodegenerative phenotype

〇Masato Mashimo^1,2, Xiangning Bu², Kazumasa Aoyama², Jiro Kato², Hiroko Ishiwata-Endo², Linda A. Stevens², Atsushi Kasamatsu^2,5, Lynne A. Wolfe³, Camilo Toro³, David Adams^3,4, Thomas Markello³, William A. Gahl^3,4, Joel Moss² (1.Dept. of Pharmacol., Fac. of Pharm. Sci., Doshisha Womens College, 2.Pulmonary Branch, NHLBI, NIH, 3.NIH Undiagnosed Diseases Program, Common Fund, Office of the Director, NIH, 4.Office of the Clinical Director, NHGRI, NIH, 5.Dept. of Oral Sci., Grad. Sch. of Med., Chiba Univ.)

Programmed cell death, ADP-ribosylation